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Russia approves first COVID-19 Coronavirus prescription drug for sale

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MOSCOW: Russia has approved R-Pharm`s Coronavir treatment for outpatients with mild to moderate COVID-19 infections and the antiviral drug could be rolled out to pharmacies in the country as soon as next week, the company said on Friday. Coronavir`s approval as a prescription drug follows the green light for another Russian COVID-19 drug, Avifavir, in May. Both are based on favipiravir, which was developed in Japan and is widely used there as the basis for viral treatments.

R-Pharm`s announcement is another sign Russia is pushing hard to take a global lead in the race against the virus. It is already exporting its COVID-19 tests and has clinched several international deals for supplies of its Sputnik-V vaccine. R-Pharm said it received approval for Coronavir after Phase III clinical trials involving 168 patients with COVID-19.

The drug was first approved for in-hospital use to treat COVID-19 in July, a government register showed. Coronavir`s trial was comparatively small. The European health regulator on Friday endorsed the use of the steroid dexamethasone in the treatment of COVID-19 patients after a study by UK researchers on several thousand patients.

R-Pharm has started talks with pharmacies about orders, the company`s spokeswoman said, with Coronavir supplies expected to be rolled out in the near future, possibly as soon as next week. Coronavir is made at R-Pharm`s facility in Yaroslavl, about 300 km (186 miles) northeast of Moscow.

Avifavir has been available in hospitals since June but has yet to be supplied to pharmacies. Both are based on the active ingredient favipiravir, which is also the key component in Fujifilm Holdings Corp`s antiviral drug Avigan, approved in Japan as an emergency influenza treatment in 2014.

Trials to test it against COVID-19 are ongoing around the world. Results of a Japanese study in July were inconclusive. It is produced by various Indian generic drugmakers including Lupin, Cipla, and Dr. Reddy`s for use against COVID-19 in India.

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Bharat Ratna awardee and true gem Lata Mangeshkar Ji is no more

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late Lata Mangeshkar Ji

The nightingale of the music industry, Lata Mangeshkar Ji passed away on February 6 at the age of 92 in the Breach Candy Hospital in Mumbai. She was born on September 29, 1929. Very few singers have achieved the admiration that she did in her life.

She sang thousands of songs in more than 20 different languages. Not only in India, Bangladesh, Nepal, and Pakistan, she was also admired and praised in western countries.

PM Modi was among the first ones to share the sad news. “The kind and caring Lata Didi has left us. She leaves a void in our nation that cannot be filled. The coming generations will remember her as a stalwart of Indian culture, whose melodious voice had an unparalleled ability to mesmerise people,” he tweeted.

Apart from Bharat Ratna, she received numerous honors like the Daughter of the Nation award, the Legion of Honour award from the French government, and many more. Lata Mangeshkar truly was a gift that India will never cease cherishing.

We at Giveupnot pay our heartly tributes to her and wish that “unki aatma ko sadgati prapt ho”, OM SHANTI.

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A man in New Zealand finds insects in his Domino’s pizza

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insects

A man in West Auckland, New Zealand says he was left feeling sick after allegedly discovering maggots (insects larva) on his takeaway pizza order from Domino’s.  However, the Domino’s Pizza outlet where Reginald Thalari says he bought the pizza denied the claim.

On Tuesday afternoon, Thalari purchased four pizzas from Domino’s Pizza outlet in Avondale for his employees. But it was after they had eaten a few slices that Thalari alleges they made a stomach-churning discovery.

“It was disgusting. We ordered four pizzas but when we opened the box with pepperoni we saw maggots on the ham.  I felt like spewing, to be honest. If someone says would you like some pizza I think I’ll turn them down next time.”

However, a Domino’s spokesperson said that it is extremely unlikely maggots would have been in store pre-purchase and said it would be “impossible” for eggs to survive the temperature of their ovens.

“Domino’s takes food health and safety extremely seriously, and ensures these standards are upheld through regular audits and inspections of stores throughout the year,” the spokesperson said.

The Domino’s Pizza spokeswoman further said that “Upon learning of this customer’s experience, we contacted the customer directly and have organised a deep clean of the store, as well as for our pest control company to further inspect,”

Input: NZHerald

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US Northeast digs out after massive snow storm, Two dead

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US Snow

People across the U.S. Northeast were digging themselves out on Tuesday after a powerful storm blanketed parts of the region with more than 2 feet of snow, prompting airlines to cancel flights and contributing to at least two deaths.

The nor`easter – an East Coast storm whose winds blow from the northeast – cut power to thousands of households, and halted some subway and train service in and around New York City. It dropped about 30 inches (76 cm) of snow in parts of New Jersey and Pennsylvania and up to 18 inches (46 cm) in New York City.

The snowy weather was expected to continue in parts of the Northeast, with a stretch from upstate New York to northern Maine hit the hardest, the National Weather Service said in its latest forecast on Tuesday. Snow could develop in the Upper Midwest on Wednesday before the storm runs its course, it said.

In Allentown, Pennsylvania, a 67-year-old woman suffering from Alzheimer`s disease was found lying dead in the snow on Monday after wandering away from her home, police said.

A man in Newark, New Jersey, died after being found lying in the snow on Monday, according to police officials, who said the death was not considered suspicious.

In New York City, public transit was coming back to life. Outdoor subway service, which had been suspended, resumed, buses were running on reduced schedules, and the area`s major commuter railroads had resumed partial or full operations.

The city`s LaGuardia Airport and John F. Kennedy International Airport, where flights were canceled on Monday, both said they were working to clear the snow and that they expected activity to pick up later on Tuesday.

The storm prompted widespread closings of schools and COVID-19 vaccination sites. In Connecticut, about 10,000 vaccination appointments were canceled on Monday, with plans to reschedule them for later this week.

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