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Russia approves first COVID-19 Coronavirus prescription drug for sale

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MOSCOW: Russia has approved R-Pharm`s Coronavir treatment for outpatients with mild to moderate COVID-19 infections and the antiviral drug could be rolled out to pharmacies in the country as soon as next week, the company said on Friday. Coronavir`s approval as a prescription drug follows the green light for another Russian COVID-19 drug, Avifavir, in May. Both are based on favipiravir, which was developed in Japan and is widely used there as the basis for viral treatments.

R-Pharm`s announcement is another sign Russia is pushing hard to take a global lead in the race against the virus. It is already exporting its COVID-19 tests and has clinched several international deals for supplies of its Sputnik-V vaccine. R-Pharm said it received approval for Coronavir after Phase III clinical trials involving 168 patients with COVID-19.

The drug was first approved for in-hospital use to treat COVID-19 in July, a government register showed. Coronavir`s trial was comparatively small. The European health regulator on Friday endorsed the use of the steroid dexamethasone in the treatment of COVID-19 patients after a study by UK researchers on several thousand patients.

R-Pharm has started talks with pharmacies about orders, the company`s spokeswoman said, with Coronavir supplies expected to be rolled out in the near future, possibly as soon as next week. Coronavir is made at R-Pharm`s facility in Yaroslavl, about 300 km (186 miles) northeast of Moscow.

Avifavir has been available in hospitals since June but has yet to be supplied to pharmacies. Both are based on the active ingredient favipiravir, which is also the key component in Fujifilm Holdings Corp`s antiviral drug Avigan, approved in Japan as an emergency influenza treatment in 2014.

Trials to test it against COVID-19 are ongoing around the world. Results of a Japanese study in July were inconclusive. It is produced by various Indian generic drugmakers including Lupin, Cipla, and Dr. Reddy`s for use against COVID-19 in India.

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London Bridge Down: Death of Queen Elizabeth brings a moment of reckoning for Britain

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queen elizabeth ii

LONDON: Queen Elizabeth II has died in Scotland aged 96 after battling health problems since last October, the Royal Family announced Thursday. Doctors had placed the queen under medical supervision at Balmoral Castle, her estate in the Scottish Highlands.

Buckingham Palace has just released the following statement: “The Queen died peacefully at Balmoral this afternoon. The King and The Queen Consort will remain at Balmoral this evening and will return to London tomorrow.”

Her close family rushed to her bedside as doctors grew “concerned” about her health on Thursday, Buckingham Palace said. Her grandson and his wife, Harry and Meghan Markle – who had a public showdown with the Palace, flew in from Canada.

According to news agency AFP, the Queen pulled out of a planned meeting with her senior political advisors on Wednesday, after being told to rest. The previous day she had audiences at Balmoral – her Scottish Highlands retreat, with outgoing Prime Minister Boris Johnson and appointed his successor, Liz Truss.

In recent months, the Queen appeared visibly frail and had a series of withdrawals from public engagements. She had taken to walking with a stick and was also seen touring the Chelsea Flower Show in a motorized buggy.

In June, the UK came together for the Platinum Jubilee celebrations to mark the 70th anniversary of the Queen’s accession to the British throne. Her husband, Prince Phillip, died last year at the age of 99, two months before his 100th birthday.

Queen Elizabeth II’s tenure as head of state spanned post-war austerity, the transition from empire to Commonwealth, the end of the Cold War and the UK’s entry into – and withdrawal from – the European Union.

Her reign spanned 15 prime ministers starting with Winston Churchill, born in 1874, and including Liz Truss, born 101 years later in 1975, and appointed by the Queen earlier this week. She held weekly audiences with her prime minister throughout her reign.

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Bharat Ratna awardee and true gem Lata Mangeshkar Ji is no more

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late Lata Mangeshkar Ji

The nightingale of the music industry, Lata Mangeshkar Ji passed away on February 6 at the age of 92 in the Breach Candy Hospital in Mumbai. She was born on September 29, 1929. Very few singers have achieved the admiration that she did in her life.

She sang thousands of songs in more than 20 different languages. Not only in India, Bangladesh, Nepal, and Pakistan, she was also admired and praised in western countries.

PM Modi was among the first ones to share the sad news. “The kind and caring Lata Didi has left us. She leaves a void in our nation that cannot be filled. The coming generations will remember her as a stalwart of Indian culture, whose melodious voice had an unparalleled ability to mesmerise people,” he tweeted.

Apart from Bharat Ratna, she received numerous honors like the Daughter of the Nation award, the Legion of Honour award from the French government, and many more. Lata Mangeshkar truly was a gift that India will never cease cherishing.

We at Giveupnot pay our heartly tributes to her and wish that “unki aatma ko sadgati prapt ho”, OM SHANTI.

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A man in New Zealand finds insects in his Domino’s pizza

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A man in West Auckland, New Zealand says he was left feeling sick after allegedly discovering maggots (insects larva) on his takeaway pizza order from Domino’s.  However, the Domino’s Pizza outlet where Reginald Thalari says he bought the pizza denied the claim.

On Tuesday afternoon, Thalari purchased four pizzas from Domino’s Pizza outlet in Avondale for his employees. But it was after they had eaten a few slices that Thalari alleges they made a stomach-churning discovery.

“It was disgusting. We ordered four pizzas but when we opened the box with pepperoni we saw maggots on the ham.  I felt like spewing, to be honest. If someone says would you like some pizza I think I’ll turn them down next time.”

However, a Domino’s spokesperson said that it is extremely unlikely maggots would have been in store pre-purchase and said it would be “impossible” for eggs to survive the temperature of their ovens.

“Domino’s takes food health and safety extremely seriously, and ensures these standards are upheld through regular audits and inspections of stores throughout the year,” the spokesperson said.

The Domino’s Pizza spokeswoman further said that “Upon learning of this customer’s experience, we contacted the customer directly and have organised a deep clean of the store, as well as for our pest control company to further inspect,”

Input: NZHerald

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