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Government expert group reviews 3 Covid-19 vaccines in India

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COVID-19 Vaccine

COVID-19 Vaccine

New Delhi: The National Expert Group on Vaccine Administration Monday met with five domestic COVID-19 vaccine manufacturers, including two whose products are not yet in the clinical trial stages in India, to review the situation.

The two companies are Gennova Biopharmaceuticals, based in Pune, and Biological E in Hyderabad. The remaining three are the Serum Institute of India, Bharat Biotech, and Zydus Cadila, all of whose vaccines are in different stages of a clinical trial.

According to a government statement on Monday’s expert group meeting: “It provided the National Expert Group with inputs about the present stage of various candidate vaccines being developed by the indigenous manufacturers as well as their expectations from the Union Government.”

Gennova Biopharmaceuticals, in collaboration with HDT Biotech Corporation in Seattle, USA, has developed an mRNA vaccine candidate (HGCO19) with “demonstrated safety, immunogenicity, neutralization antibody activity in the rodent and non-human primate models”.

“The company is working aggressively to ensure first human injection by the end of the year, subject to Indian regulatory approvals,” a PIB statement issued last month stated while announcing a tie-up of the Department of Biotechnology (DBT) with the company.

The DBT Biotechnology Industry Research Assistance Council (DBT-BIRAC) had facilitated the establishment of a ‘first-of-its-kind’ mRNA-based vaccine manufacturing platform in India. DBT provided seed funding for the development of Gennova’s novel self-amplifying mRNA-based vaccine candidate for Covid-19, the statement had said.

As for Biological E, the company just announced a tie-up with Johnson & Johnson. In its statement on 13 August, the company said: “Biological E. Limited (“BE”) has entered into an agreement with Janssen Pharmaceutica NV (“Janssen”), one of the Janssen Pharmaceutical Companies of Johnson & Johnson, for the creation/enhancement of manufacturing capacities for drug substance and drug product for Johnson & Johnson’s COVID-19 vaccine candidate, Ad26.COV2.S. Johnson & Johnson’s COVID-19 vaccine candidate is currently in Phase 1/2a clinical trials.”

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Instagram Down: Giving 5xx Server Error

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Instagram

Update 19 Mar 2021 23:38 IST: Instagram and other apps are now working fine.

Instagram is currently facing downtime and users from all around the world are reporting Instagram Server Down on Twitter. Some users are also facing downtime on WhatsApp and Facebook Messenger.

The Instagram app is showing “couldn’t refresh feed”. and the Instagram website is giving 5xx Server Error.

Server Error on Instagram Website

Server Error on Instagram Website

 

Server Error on Instagram Mobile App

Server Error on Instagram Mobile App

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Earthquake in Nalanda, Patna – Bihar with 3.5 Magnitude

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Earthquae

An earthquake of magnitude 3.5 was reported near Nalanda in Bihar on Monday night, according to India’s National Center for Seismology.

The epicenter of the earthquake was 20 km northwest (NW) of Nalanda, Bihar, India, the agency said. The earthquake struck at 9:23 PM IST at a depth of 5 km from the surface. Tremors were also felt in Gaya, Bhagalpur, Nalanda, Patna.

Earthquake Areas

Earthquake Areas

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Uttarakhand Power Plant Damaged After The Glacier Burst

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Chamoli Glacier Burst

Uttarakhand: A glacial burst in Chamoli district, Uttarakhand triggered an avalanche and massive flooding of the Alaknanda and Dhauliganga rivers on Sunday morning, forcing the emergency evacuation of thousands from surrounding areas, and damaging houses and the nearby Rishiganga power project.

Disaster response and management teams have been deployed to conduct search-and-rescue and relief operations. Around 100 to 150 people may have been killed, Uttarakhand Chief Secretary Om Prakash told news agency ANI. Authorities fear hundreds more may still be stuck. Prime Minister Narendra Modi, who is in Assam to campaign for Assembly polls, tweeted: “India stands with Uttarakhand and the nation prays for everyone’s safety.”

Disaster management teams have been mobilized and hundreds of ITBP (Indo-Tibetan Border Police) have been rushed for rescue operations.

SN Pradhan, chief of the National Disaster Response Force (NDRF), said that teams from the relief force have been moved for search-and-rescue and relief operations in Uttarakhand where a glacial burst has triggered an avalanche. “The glacial burst has taken out a bridge constructed by the Border Road Organisation. Also in the higher reaches, the Rishiganga hydel project also has been damaged,” he said.

 

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