After striking down the first proposal, the Drug Controller General of India has finally allowed Dr. Reddy’s to conduct phase 2/3 clinical human trial of Sputnik V, the Covid-19 vaccine that makes Russia the first country to have come up with a vaccine.
“This will be a multi-center and randomized controlled study, which will include safety and immunogenicity study,” a joint statement issued by Dr. Reddy’s and Russian Direct Investment Fund (RDIF) said.
Since Sputnik V was tested on a small number of people in Russia before it got registered as a vaccine, the DCGI raised questions over Dr. Reddy’s initial proposal of testing it among a bigger population in India. At present, Sputnik V is currently undergoing a post-registration phase 3 clinical trial engaging 40,000 participants.
In September, Dr. Reddy’s and RDIF entered into a partnership to conduct clinical trials of the Sputnik V vaccine and its distribution in India. As part of the partnership, India will get 100 million doses of Sputnik.
“We acknowledge DCGI’s scientific rigor and guidance in the entire process. This is a significant development that allows us to commence the clinical trial in India and we are committed to bringing in a safe and efficacious vaccine to combat the pandemic,” G V Prasad, co-chairman and managing director, Dr. Reddy’s Laboratories, said.
On August 11, the Sputnik V vaccine developed by the Gamaleya National Research Institute of Epidemiology and Microbiology was registered by the Ministry of Health of Russia and became the world’s first registered vaccine against COVID-19 based on the human adenoviral vectors platform.
A second vaccine — EpiVacCorona — has been registered in Russia. The third vaccine has received permission to conduct the first and second stages of clinical trials at medical facilities in Novosibirsk, St Petersburg, and Kirov. During the first stage, 15 volunteers were inoculated with this vaccine on October 6.
Instagram Down: Giving 5xx Server Error
Update 19 Mar 2021 23:38 IST: Instagram and other apps are now working fine.
Instagram is currently facing downtime and users from all around the world are reporting Instagram Server Down on Twitter. Some users are also facing downtime on WhatsApp and Facebook Messenger.
The Instagram app is showing “couldn’t refresh feed”. and the Instagram website is giving 5xx Server Error.
Earthquake in Nalanda, Patna – Bihar with 3.5 Magnitude
An earthquake of magnitude 3.5 was reported near Nalanda in Bihar on Monday night, according to India’s National Center for Seismology.
The epicenter of the earthquake was 20 km northwest (NW) of Nalanda, Bihar, India, the agency said. The earthquake struck at 9:23 PM IST at a depth of 5 km from the surface. Tremors were also felt in Gaya, Bhagalpur, Nalanda, Patna.
Uttarakhand Power Plant Damaged After The Glacier Burst
Uttarakhand: A glacial burst in Chamoli district, Uttarakhand triggered an avalanche and massive flooding of the Alaknanda and Dhauliganga rivers on Sunday morning, forcing the emergency evacuation of thousands from surrounding areas, and damaging houses and the nearby Rishiganga power project.
Disaster response and management teams have been deployed to conduct search-and-rescue and relief operations. Around 100 to 150 people may have been killed, Uttarakhand Chief Secretary Om Prakash told news agency ANI. Authorities fear hundreds more may still be stuck. Prime Minister Narendra Modi, who is in Assam to campaign for Assembly polls, tweeted: “India stands with Uttarakhand and the nation prays for everyone’s safety.”
Disaster management teams have been mobilized and hundreds of ITBP (Indo-Tibetan Border Police) have been rushed for rescue operations.
SN Pradhan, chief of the National Disaster Response Force (NDRF), said that teams from the relief force have been moved for search-and-rescue and relief operations in Uttarakhand where a glacial burst has triggered an avalanche. “The glacial burst has taken out a bridge constructed by the Border Road Organisation. Also in the higher reaches, the Rishiganga hydel project also has been damaged,” he said.